LeptonX Standards Division

Setting the bar
for local medical AI.

As a first-mover in private, on-device medical intelligence, LeptonX leads the standards conversation — from retrieval benchmarking to data residency protocols to clinical AI evaluation frameworks.

IEC Aligned ISO/IEC 42001 IEEE Contributor NIST 800-53
Standards Alignment

Internationally grounded.

LeptonX standards proposals are developed in alignment with the world's leading standards bodies.

IEC

International Electrotechnical Commission

AI system safety, reliability, and edge computing deployment in regulated environments.

ISO

International Organization for Standardization

ISO/IEC 42001 AI Management Systems and ISO 27001 as applied to local medical AI.

IEEE

Institute of Electrical and Electronics Engineers

IEEE P2863 and IEEE 11073 contributions for local AI clinical applications.

ITU

International Telecommunication Union

ITU-T AI/ML standards for trustworthy AI and data sovereignty in personal device contexts.

ANSI

American National Standards Institute

U.S. standards coordination for clinical AI processing pipelines and on-premise medical AI deployment.

NIST

National Institute of Standards & Technology

Full alignment with NIST AI RMF and NIST 800-53 security controls for medical AI system deployment.

LeptonX Proposed Standards

Leading the definition.

LeptonX is authoring standards proposals across five domains of local medical AI.

LPX-MED-001
Local Medical RAG Evaluation Framework

Standardized benchmark methodology for evaluating retrieval-augmented generation systems on clinical oncology query sets. Defines scoring rubrics, query taxonomy, and minimum accuracy thresholds.

Active
LPX-MED-002
PHI Data Residency Certification

Certification protocol for verifying that medical AI systems process protected health information exclusively on-device with zero external data transmission.

Proposed
LPX-MED-003
Clinical Voice AI Quality Standard

Evaluation criteria for voice-based clinical AI including pronunciation accuracy, response latency, empathetic framing, and clinical precision.

Draft
LPX-GEN-001
Genomic Data Sovereignty Protocol

Framework for patient-controlled storage and querying of VCF/FASTQ genomic files on personal hardware. Defines encryption standards, access controls, and portability requirements.

Proposed
LPX-AI-001
Medical Ontology Compression Standard

Specification for UMLS/SNOMED-CT/RxNorm-based vocabulary compression enabling higher retrieval density while maintaining clinical semantic fidelity.

Draft
LPX-MOB-001
Ephemeral Mobile Health Container Spec

Technical specification for secure, read-only, time-bounded mobile AI containers for offline clinical use. Covers encryption, model quantization, lifecycle management.

Draft
Performance Benchmarks

Measured against ourselves.

LeptonX publishes transparent benchmark data across all query dimensions. Methodology is open and reproducible.

Radar — All Dimensions

v1 baseline vs v2 production pipeline (all fixes applied)

v1 (80.0%)
v2 (94.6% mean)
Per-Dimension Accuracy

44-query suite · 6,602 document chunks

94.6%
Labs / Hematology100%
Research Literature100%
Adverse Events100%
Treatment Protocols96%
Molecular Markers87%
Recency / Temporal90%
IHC Pathology80%
Imaging / Radiology100%
Surgical / Procedures100%
Provider / Care Team100%
Quality of Life100%
Semantic / Conceptual100%
v1: 144/180 (80.0%) → v2: 94.6% meanv2: 168–172/180 (93–96%)
Benchmark Trajectory — Projected Roadmap
80%
Phase 1 ✓

Foundation

91%
Phase 2 ✓

Corpus Cleaning

94%
Phase 3

Doc Compression

96%
Phase 4

UMLS Encoding

97%
Phase 5+

Voice + Mobile

Full Dimension Breakdown — v1 vs v2
Dimension v1 Score v2 Score Improvement Status
Labs / Hematology11/1515/15▲ +4Resolved
Research Literature19/2121/21▲ +2Resolved
Adverse Events13/1515/15▲ +2Resolved
Treatment Protocols23/2424/24▲ +1Resolved
Molecular Markers9/1513/15▲ +4In Progress
IHC Pathology6/108/10▲ +2 (Phase 2b)In Progress
Recency / Temporal16/2018/20▲ +2 (Phase 2b)Planned
Imaging / Radiology8/159/15▲ +1Planned
TOTAL 146/180 164/180 ▲ +18 (+10%)